Depends on the IV distribution, and your goal.
Want high CP? Go for highest Att IV.
Want maximum tankiness? Go for highest Def IV.
Stam IV won't have a big impact on Blissey.
Based on movesets, it seems like the general consensus is that the quick moves are more or less the same, DG is the best charge move, HB is also quite good, and Psy is suboptimal. But it also depends on whether you think Blissey's damage output or her tankiness is what's important.