Personally I'd go with 3-4 Tyranitar and the rest of the lineup resistant to fighting. Even if Mewtwo does have Focus Blast, a Tyranitar should still get a decent amount of damage done, and the other 2-3 Pokemon can survive long enough to finish the raid, and if the Mewtwo has any other charge move, then 3-4 Tyranitars is probably all you'll need anyway.
I think people are forgetting that raids are about damage, and Tyranitar still does a lot of it even if it does faint quickly to Focus Blast.
People don't bat an eye when someone brings a Gengar that dies in 20 seconds and only gets one Shadow Ball off, but somehow think that Tyranitar is a bad choice because it gets one shot by Focus Blast.