Huh, this looks really bad. Ultra League level Giratina bad.
Currently, the Great League does not suffer from the dominance of single pokemon the way Ultra League suffers from Giratina. And it seemed that it should be able to avoid that danger due to the sheer number of viable pokemons there. Even Giratina wouldn't cause as much havoc, as the Great Leauge has a decent number of usable counters - Azumarril, Wigglytuff or even Mawile.
But, enter Deoxys Defense. Being a pure Psychic and having access to Counter and two very powerful charge moves - Psycho Boost and Rock Slide - gives it super wide type coverage that hardly any counter can slip within.
Looks like the only viable counters will be Ghosts (with some possible secondary typing), as no Dark pokemon will stand a chance against Counter, while some Bugs might get into rough parity against Rock Slide, but Deoxys' DEF might still prevail.
Well, Giratina could help, but if Deoxys arrives first, we might see a lot of Dusclops, Spiritombs and maybe Alolan Muks just to stay alive.